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Dimethocaine is a local anesthetic that, because of its similarity in action to c0caine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 µM comparable to c0caine .
What is dimethocaine used for?
During the 1930s dimethocaine gained popularity in the US as a local anesthetic. Just like c0caine and procaine, it was used during surgery, primarily in dentistry, ophthalmology and otolaryngology. However, in the 1940s, it was removed from the market because of its psychoactive effects and risk of addiction.
Is procaine the same as novocaine?
procaine hydrochloride, also called Novocain, or Novocaine, synthetic organic compound used in medicine as a local anesthetic. Introduced in 1905 under the trade name Novocaine, it became the first and best-known substitute for c0caine in local anesthesia.