Tri Luma Cream (Hydroquinone + Tretinoin + Fluocinolone acetonide) | Lumacip Plus | Treat Melasma

Tri-Luma Cream is a prescription topical medication specifically formulated to treat moderate to severe facial melasma. It combines three active ingredients: hydroquinone 4%, tretinoin 0.05%, and fluocinolone acetonide 0.01%. This triple combination works synergistically to lighten hyperpigmented areas, promote skin cell turnover, and reduce inflammation. Tri-Luma is the only FDA-approved fixed-dose combination cream for melasma and is intended for short-term use, typically up to 8 weeks.

Hydroquinone (4%): Acts as a depigmenting agent by inhibiting melanin production, thereby lightening dark patches on the skin .

Tretinoin (0.05%): A retinoid that accelerates skin cell turnover, helping to remove pigmented cells and enhance the penetration of hydroquinone .

Fluocinolone Acetonide (0.01%): A mild corticosteroid that reduces inflammation and minimizes potential irritation from the other two ingredients

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